A: The story started with claims that Nibiru, a supposed planet discovered by the Sumerians, is headed toward Earth. This catastrophe was initially predicted for May 2003, but when nothing happened the doomsday date was moved forward to December 2012. Then these two fables were linked to the end of one of the cycles in the ancient Mayan calendar at the winter solstice in 2012 -- hence the predicted doomsday date of December 21, 2012.
A: There are no planetary alignments in the next few decades, Earth will not cross the galactic plane in 2012, and even if these alignments were to occur, their effects on the Earth would be negligible. Each December the Earth and sun align with the approximate center of the Milky Way Galaxy but that is an annual event of no consequence.